Ruocco's immunocompromised cutaneous district.
Identifieur interne : 000B46 ( Main/Exploration ); précédent : 000B45; suivant : 000B47Ruocco's immunocompromised cutaneous district.
Auteurs : Vincenzo Piccolo [Italie] ; Adone Baroni [Italie] ; Teresa Russo [Italie] ; Robert A. Schwartz [États-Unis]Source :
- International journal of dermatology [ 1365-4632 ] ; 2016.
Descripteurs français
- KwdFr :
- Brûlures (immunologie), Eczéma de contact (immunologie), Herpès (immunologie), Humains, Lymphoedème (), Maladies de la peau (immunologie), Moignons d'amputation, Peau (effets des radiations), Peau (immunologie), Peau (physiopathologie), Sujet immunodéprimé, Tatouage, Ulcère variqueux (), Vaccination.
- MESH :
- effets des radiations : Peau.
- immunologie : Brûlures, Eczéma de contact, Herpès, Maladies de la peau, Peau.
- physiopathologie : Peau.
- Humains, Lymphoedème, Moignons d'amputation, Sujet immunodéprimé, Tatouage, Ulcère variqueux, Vaccination.
English descriptors
- KwdEn :
- Amputation Stumps, Burns (immunology), Dermatitis, Contact (immunology), Herpes Simplex (immunology), Humans, Immunocompromised Host, Lymphedema (complications), Skin (immunology), Skin (physiopathology), Skin (radiation effects), Skin Diseases (immunology), Tattooing, Vaccination, Varicose Ulcer (complications).
- MESH :
- complications : Lymphedema, Varicose Ulcer.
- immunology : Burns, Dermatitis, Contact, Herpes Simplex, Skin, Skin Diseases.
- physiopathology : Skin.
- radiation effects : Skin.
- Amputation Stumps, Humans, Immunocompromised Host, Tattooing, Vaccination.
Abstract
The concept of 'locus minoris resistentiae' (lmr) is an old but still effective way of thinking in Medicine. In Dermatology, there are many reports of privileged localization of cutaneous diseases on injured skin, which therefore represents a typical condition of lmr. Lately the innovative concept of immunocompromised cutaneous district (ICD) has been introduced to explain why a previously injured cutaneous site may become in time a privileged location for the outbreak of opportunistic infections, tumors, and immune reactions. An ample documentation of multifarious disorders (infectious, neoplastic, immune) appearing in ICDs was delineated by Ruocco et al. in 2009. These cases were grouped according to the clinical settings responsible for the local immune imbalance: regional chronic lymphedema; herpes-infected sites, which feature the well-known Wolf's isotopic response; and otherwise damaged areas, comprising sites of vaccination, ionizing or UV radiation, thermal burns, and traumas. In the following five years, what was a "novel" pathogenic concept has been extended to an enlarging variety of clinical conditions. This paper focuses on ICD and the expanding spectrum of this now established pathogenic concept.
DOI: 10.1111/ijd.13086
PubMed: 26475059
Affiliations:
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Le document en format XML
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Schwartz</name><affiliation wicri:level="2"><nlm:affiliation>Dermatology and Pathology, Rutgers New Jersey Medical School, Newark, NJ, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Dermatology and Pathology, Rutgers New Jersey Medical School, Newark, NJ</wicri:regionArea><placeName><region type="state">New Jersey</region></placeName></affiliation></author></analytic><series><title level="j">International journal of dermatology</title><idno type="eISSN">1365-4632</idno><imprint><date when="2016" type="published">2016</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Amputation Stumps</term><term>Burns (immunology)</term><term>Dermatitis, Contact (immunology)</term><term>Herpes Simplex (immunology)</term><term>Humans</term><term>Immunocompromised Host</term><term>Lymphedema (complications)</term><term>Skin (immunology)</term><term>Skin (physiopathology)</term><term>Skin (radiation effects)</term><term>Skin Diseases (immunology)</term><term>Tattooing</term><term>Vaccination</term><term>Varicose Ulcer (complications)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Brûlures (immunologie)</term><term>Eczéma de contact (immunologie)</term><term>Herpès (immunologie)</term><term>Humains</term><term>Lymphoedème ()</term><term>Maladies de la peau (immunologie)</term><term>Moignons d'amputation</term><term>Peau (effets des radiations)</term><term>Peau (immunologie)</term><term>Peau (physiopathologie)</term><term>Sujet immunodéprimé</term><term>Tatouage</term><term>Ulcère variqueux ()</term><term>Vaccination</term></keywords><keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Lymphedema</term><term>Varicose Ulcer</term></keywords><keywords scheme="MESH" qualifier="effets des radiations" xml:lang="fr"><term>Peau</term></keywords><keywords scheme="MESH" qualifier="immunologie" xml:lang="fr"><term>Brûlures</term><term>Eczéma de contact</term><term>Herpès</term><term>Maladies de la peau</term><term>Peau</term></keywords><keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>Burns</term><term>Dermatitis, Contact</term><term>Herpes Simplex</term><term>Skin</term><term>Skin Diseases</term></keywords><keywords scheme="MESH" qualifier="physiopathologie" xml:lang="fr"><term>Peau</term></keywords><keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Skin</term></keywords><keywords scheme="MESH" qualifier="radiation effects" xml:lang="en"><term>Skin</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Amputation Stumps</term><term>Humans</term><term>Immunocompromised Host</term><term>Tattooing</term><term>Vaccination</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Humains</term><term>Lymphoedème</term><term>Moignons d'amputation</term><term>Sujet immunodéprimé</term><term>Tatouage</term><term>Ulcère variqueux</term><term>Vaccination</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The concept of 'locus minoris resistentiae' (lmr) is an old but still effective way of thinking in Medicine. In Dermatology, there are many reports of privileged localization of cutaneous diseases on injured skin, which therefore represents a typical condition of lmr. Lately the innovative concept of immunocompromised cutaneous district (ICD) has been introduced to explain why a previously injured cutaneous site may become in time a privileged location for the outbreak of opportunistic infections, tumors, and immune reactions. An ample documentation of multifarious disorders (infectious, neoplastic, immune) appearing in ICDs was delineated by Ruocco et al. in 2009. These cases were grouped according to the clinical settings responsible for the local immune imbalance: regional chronic lymphedema; herpes-infected sites, which feature the well-known Wolf's isotopic response; and otherwise damaged areas, comprising sites of vaccination, ionizing or UV radiation, thermal burns, and traumas. In the following five years, what was a "novel" pathogenic concept has been extended to an enlarging variety of clinical conditions. This paper focuses on ICD and the expanding spectrum of this now established pathogenic concept.</div></front></TEI><affiliations><list><country><li>Italie</li><li>États-Unis</li></country><region><li>New Jersey</li></region></list><tree><country name="Italie"><noRegion><name sortKey="Piccolo, Vincenzo" sort="Piccolo, Vincenzo" uniqKey="Piccolo V" first="Vincenzo" last="Piccolo">Vincenzo Piccolo</name></noRegion><name sortKey="Baroni, Adone" sort="Baroni, Adone" uniqKey="Baroni A" first="Adone" last="Baroni">Adone Baroni</name><name sortKey="Russo, Teresa" sort="Russo, Teresa" uniqKey="Russo T" first="Teresa" last="Russo">Teresa Russo</name></country><country name="États-Unis"><region name="New Jersey"><name sortKey="Schwartz, Robert A" sort="Schwartz, Robert A" uniqKey="Schwartz R" first="Robert A" last="Schwartz">Robert A. 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